GI Microbiota and Regulation of the Immune System PDF ePub eBook

Books Info:

GI Microbiota and Regulation of the Immune System free pdf The idea that the microbial communities within the GI tract have a profound influence on general human health actually originated with Russian scientist Elie Metchnikov at the turn ofthe last century. Also known as the "fatherofimmunol- ogy", Metchnikovbelievedthat putrefactivebacteriain the gut were responsible for enhancing the aging process. He theorized that ingestion ofhealthy bacteria found in fermented foods could counteract toxic bacteria and was the key to good health. His theories concerning good bacteria and health can be found in his treatise "The ProlongationofLife: Optimistic Studies".Thesewritings promptedJapanesescientist Minoru Shirotatobegin investigationofhow fermentative bacteriaimprove health. He succeededin isolating astrainofLactobacillusthat could survive passage through the intestine, while promoting a healthy balance ofmicrobes. The "Shirota strain" is still used today in the fermented beverage Yakult.It is clear from a commercial standpoint that these ideas have inspired the development of a probiotic industry, which has expanded greatly in the U.S. over the past 5-10 years.

About Dr. Gary B. Huffnagle

Gary B. Huffnagle, PhD, is a Professor of Internal Medicine (Pulmonary Diseases) and Microbiology and Immunology at the University of Michigan Medical School. He holds a BS in microbiology from Pennsylvania State University and a PhD in immunology from the University of Texas Southwestern Medical School. In addition to conducting research, he teaches undergraduate and graduate classes in eukaryotic microbiology, microbial symbiosis and experimental immunology at the University of Michigan. Dr. Huffnagle's research focuses on the regulation of pulmonary immunity to infectious agents and allergens. In the past 5 years, his attention has turned to the role of the indigenous microbiota in immune system functioning, as well as the role of probiotics in animal and human health. He has been awarded research grants from the National Heart, Lung and Blood Institute (NHL BI), National Institute of Allergy and Infectious Diseases (NIAID), the Francis Families Foundation and the Burroughs-Wellcome Fund. Dr. Huffnagle serves or has served on editorial boards for the American Society for Microbiology (ASM) and the American Association of Immunologists (AAI), as well as on advisory and review panels for the National Institutes of Health (NIH). Mairi C. Nove rr, PhD, is an Assistant Professor of Immunology and Microbiology at Wayne State University Medical School. She earned a BA in biology from Kalamazoo College in 1996 and a PhD in microbiology and immunology from the University of Michigan in 2002. Dr. Noverr's current research focuses on investigating mechanisms of immunomodulation by the opportunistic yeast Candida albicans during host-pathogen interactions and how interactions with other members of the microbiota influence these interactions. Her laboratory is investigating signaling compounds called oxylipins that are produced by both Candida and the host, which can influence the microbiology of the fungus and the activity of host immune system cells. Projects in the laboratory include molecular characterization of the fungal oxylipin biosynthetic pathways and determining the effects of oxylipins during Candida pathogenesis, in modulating host immune cell function, and during fungal-bacterial interactions. She has been awarded research funding from the Francis Families Foundation.

Details Book

Author : Dr. Gary B. Huffnagle
Publisher : Springer-Verlag New York Inc.
Data Published : 01 December 2014
ISBN : 1489988165
EAN : 9781489988164
Format Book : PDF, Epub, DOCx, TXT
Number of Pages : 149 pages
Age + : 15 years
Language : English
Rating :

Reviews GI Microbiota and Regulation of the Immune System



17 Comments Add a comment




Related eBooks Download


  • The Complete Prebiotic and Probiotic Health Guide free pdfThe Complete Prebiotic and Probiotic Health Guide

    Did you know that the gut contains over 100 trillion bacteria. In recent years. there has been a great deal of research exploring the relationship between maintaining an optimal balance of healthy bacteria in our gut..


  • Good Gut Bugs free pdfGood Gut Bugs

    Did you know that there are more bacteria in your gut than the total number of cells in your body. Do you know why the good bacteria - or probiotics - are good for you and how they can benefit many aspects of your health..


  • Fermenting Vol. 4: Water Kefir free pdfFermenting Vol. 4: Water Kefir

    Water kefir is a delicious fermented beverage that's packed full of probiotic cultures. Water kefir is a fermented drink that's easy to prepare and is a delicious way to add beneficial bacteria to your diet..


  • Healthy Bowel Healthy Body free pdfHealthy Bowel Healthy Body

    New research has found gut health to play a crucial role in all aspects of health and have a profound influence on: Mental health. Energy levels. Risk of cancer- Autoimmune disease. Allergies. Weight gain..


  • General Combo Looseleaf Your Health Today with Livewell free pdfGeneral Combo Looseleaf Your Health Today with Livewell

    It s not just Personal. "Your Health Today" teaches Personal Health from a truly inclusive and socially responsible perspective. While each of us has a unique set of individual characteristics that shape our health..


  • GI Microbiota and Regulation of the Immune System free pdfGI Microbiota and Regulation of the Immune System

    . The idea that the microbial communities within the GI tract have a profound influence on general human health actually originated with Russian scientist Elie Metchnikov at the turn ofthe last centur