Cluster Randomised Trials PDF ePub eBook

Books Info:

Cluster Randomised Trials free pdf Cluster Randomised Trials discusses the design, conduct, and analysis of health trials that randomise groups of individuals to different treatments. It explores the advantages of cluster randomization, with special attention given to evaluating the effects of interventions against infectious diseases. Avoiding unnecessary mathematical detail, the book covers basic concepts underlying the use of cluster randomisation, such as direct, indirect, and total effects. The authors also present an array of design issues in cluster randomised trials (CRTs), including strategies for minimizing contamination effects, the use of stratification and restricted randomisation to improve balance between treatment arms, special methods for sample size calculation, and alternatives to the simplest two-arm CRT. After covering analytical methods for CRTs, such as regression methods, the authors examine ethical issues, trial monitoring, interim analyses, reporting, and interpretation. Although the book mainly focuses on medical and public health applications, it shows that the rigorous evidence of intervention effects provided by CRTs has the potential to inform public policy in a wide range of other areas. The book encourages readers to apply the methods to their own trials, reproduce the analyses presented, and explore alternative approaches.

About Richard J. Hayes

London School of Hygiene

Details Book

Author : Richard J. Hayes
Publisher : Chapman
Data Published : 15 November 2008
ISBN : 1584888164
EAN : 9781584888161
Format Book : PDF, Epub, DOCx, TXT
Number of Pages : 338 pages
Age + : 15 years
Language : English
Rating :

Reviews Cluster Randomised Trials



17 Comments Add a comment




Related eBooks Download


  • Randomised Response-Adaptive Designs in Clinical Trials free pdfRandomised Response-Adaptive Designs in Clinical Trials

    Randomised Response-Adaptive Designs in Clinical Trials presents methods for the randomised allocation of treatments to patients in sequential clinical trials. Emphasizing the practical application of clinical trial designs..


  • Introduction to Statistical Methods for Clinical Trials free pdfIntroduction to Statistical Methods for Clinical Trials

    Clinical trials have become essential research tools for evaluating the benefits and risks of new interventions for the treatment and prevention of diseases. from cardiovascular disease to cancer to AIDS..


  • Design and Analysis of Quality of Life Studies in Clinical Trials free pdfDesign and Analysis of Quality of Life Studies in Clinical Trials

    Design Principles and Analysis Techniques for HRQoL Clinical Trials SAS. R. and SPSS examples realistically show how to implement methods Focusing on longitudinal studies. Design and Analysis of Quality of Life Studies in Clinical Trials..


  • Power Analysis of Trials with Multilevel Data free pdfPower Analysis of Trials with Multilevel Data

    Power Analysis of Trials with Multilevel Data covers using power and sample size calculations to design trials that involve nested data structures. The book gives a thorough overview of power analysis that details terminology and notation..


  • Research Methods in Health free pdfResearch Methods in Health

    This bestselling book provides an accessible introduction to the concepts and practicalities of research methods in health and health services. This new edition has been extensively re-worked and expanded and now includes expanded coverage of: Qualitative methods Social research Evaluation methodology Mixed methods Secondary data analysis Literature reviewing and critical appraisal Evidence based practiceCovering all core methodologies in detail the book looks at the following kinds of health research: health needs morbidity and mortality trends and rates costing health services sampling for survey research cross-sectional and longitudinal survey design experimental methods and techniques of group assignment questionnaire design interviewing techniques coding and analysis of quantitative data methods and analysis of qualitative observational studies unstructured interviewingThe book is grounded in the author's career as a researcher on health and health service issues..


  • Cluster Randomised Trials free pdfCluster Randomised Trials

    Free Computer Ebooks Download. Cluster Randomised Trials discusses the design, conduct, and analysis of health trials that randomise groups of individuals to different treatments. It explores the adva