The Dynamic Bacterial Genome PDF ePub eBook

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The Dynamic Bacterial Genome free pdf This book provides an in-depth analysis of the mechanisms and biological consequences of genome rearrangements in bacteria. Genome rearrangements are a result of the actions of discrete genetic elements such as conjugative transposons, plasmids, phage, and non-conjugative transposons. Bacteria also contain systems to mediate genetic rearrangements such as the general recombination pathway and specialized endogenous recombination mechanisms. The biological effects of these rearrangements are far-reaching and impact on bacterial virulence, antibiotic resistance and the ability of bacteria to avoid the attentions of the host immune system (e.g. antigenic variation). These rearrangements also provide the raw material on which natural selection can act. Each chapter examines the mechanisms involved in genome rearrangements and the direct biological consequences of these events. This book is written by leading research workers and is an invaluable resource for graduate students and researchers in this field.

About Peter Mullany

Peter Mullany is a Reader in Molecular Microbiology at University College London. His main research interests are the molecular biology and molecular ecology of conjugative transposons. He has been at the forefront of this work for the past 10 years and has pioneered the genetic analysis of the important human pathogen Clostridium difficile.

Details Book

Author : Peter Mullany
Publisher : Cambridge University Press (Virtual Publishing)
Data Published : 19 December 2007
ISBN : 0511343299
EAN : 9780511343292
Format Book : PDF, Epub, DOCx, TXT
Number of Pages : 436 pages
Age + : 15 years
Language : English
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