New Gold-Catalyzed Reactions and Applications for the Synthesis of Alkaloids PDF ePub eBook

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New Gold-Catalyzed Reactions and Applications for the Synthesis of Alkaloids free pdf Ana Escribano Cuesta's thesis presents a detailed study of the inter- and intramolecular reactions of carbonyl compounds with 1,6-enynes using gold (I) complexes. An important part of the work involved streamlining the variables that allow the selective synthesis of different products such as tricyclic compounds, dihydropyrans, 1,3-dienes or cyclobutenes. The second chapter highlights the importance and difficulties in synthesising a cyclobutene subunit and the author includes a detailed description of how the products were prepared. The final chapter outlines the synthesis of lundurines using methodology developed by the author's research group for intramolecular gold-catalyzed cyclization of indoles with alkynes. The lundurine products developed in this work show significant in vitro cytoxicity toward B16 melanoma cells. The work in this thesis has led to a number of publications in high-profile chemistry journals.

About Ana Escribano Cuesta

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Details Book

Author : Ana Escribano Cuesta
Publisher : Springer International Publishing AG
Data Published : 30 August 2013
ISBN : 3319007017
EAN : 9783319007014
Format Book : PDF, Epub, DOCx, TXT
Number of Pages : 265 pages
Age + : 15 years
Language : English
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  • New Gold-Catalyzed Reactions and Applications for the Synthesis of Alkaloids free pdfNew Gold-Catalyzed Reactions and Applications for the Synthesis of Alkaloids

    . Ana Escribano Cuesta's thesis presents a detailed study of the inter- and intramolecular reactions of carbonyl compounds with 1,6-enynes using gold (I) complexes. An important part of the work invol