Synthetic Methods for Biologically Active Molecules PDF ePub eBook

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Synthetic Methods for Biologically Active Molecules free pdf This ready reference focuses on the currently available toolbox of biocatalysed reductions of C=O, C=C and formal C=N double bonds to show which transformations are reliable for use in manufacturing processes and which still require improvements and investigation. Following an introductory chapter, chapters 2-4 present the synthetic strategies which are currently available for the reduction of C=C, C=O and for reductive amination, by means of whole cell catalysts and isolated enzymes. Chapters 5-7 go on to describe the improvements achieved thus far, illustrating the versatility that is currently possible in adapting the enzymes to the requests of organic synthesis. Chapters 8-12 present the improvements brought about by the optimization of reaction conditions, and the use of particular synthetic sequences. The final two chapters describe the actual practical applications of bioreductions for the synthesis of active pharmaceutical ingredients, and for flavors and fragrances. With its excellent and comprehensive overview, this will be of great interest for those working in academia and industry.

About Elisabetta Brenna

Elisabetta Brenna received her laurea (1989) and PhD (1993) in chemistry from the University of Milan. In 1996, she became Assistant Professor at Politecnico di Milano, where she is now Associate Professor. Her main scientific interests are the enzyme-mediated synthesis of the single enantiomers of chiral biologically active compounds, and the use of SNIF NMR technique for tracing back the synthetic history of active pharmaceutical ingredients and flavors. She is author of more than 120 publications on international journals.

Details Book

Author : Elisabetta Brenna
Publisher : Wiley-VCH Verlag GmbH
Data Published : 29 August 2013
ISBN : 3527665803
EAN : 9783527665808
Format Book : PDF, Epub, DOCx, TXT
Number of Pages : 420 pages
Age + : 15 years
Language : English
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