Genome-Wide Association Studies and Genomic Prediction PDF ePub eBook

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Genome-Wide Association Studies and Genomic Prediction free pdf With the detailed genomic information that is now becoming available, we have a plethora of data that allows researchers to address questions in a variety of areas. Genome-wide association studies (GWAS) have become a vital approach to identify candidate regions associated with complex diseases in human medicine, production traits in agriculture, and variation in wild populations. Genomic prediction goes a step further, attempting to predict phenotypic variation in these traits from genomic information. Genome-Wide Association Studies and Genomic Prediction pulls together expert contributions to address this important area of study. The volume begins with a section covering the phenotypes of interest as well as design issues for GWAS, then moves on to discuss efficient computational methods to store and handle large datasets, quality control measures, phasing, haplotype inference, and imputation. Later chapters deal with statistical approaches to data analysis where the experimental objective is either to confirm the biology by identifying genomic regions associated to a trait or to use the data to make genomic predictions about a future phenotypic outcome (e.g. predict onset of disease). As part of the Methods in Molecular Biology series, chapters provide helpful, real-world implementation advice.

About Cedric Gondro

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Details Book

Author : Cedric Gondro
Publisher : Humana Press Inc.
Data Published : 12 June 2013
ISBN : 1627034463
EAN : 9781627034463
Format Book : PDF, Epub, DOCx, TXT
Number of Pages : 566 pages
Age + : 15 years
Language : English
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